Su etiologia es desconocida y probablemente multifactorial. Selegiline, also known as ldeprenyl and sold under the brand names eldepryl and emsam among others, is a medication which is used in the treatment of parkinson s disease and major depressive disorder. Selegiline fda prescribing information, side effects and uses. Clinical literature accessed through medline 1965 september 2002, ipa database, and drugreax. Pdf the united kingdom parkinsons disease research group ukpdrg trial found an increased mortality in patients with parkinsons. Eldepryl selegiline hydrochloride product monograph.
Rasagilina e selegilina, interazioni e tossicita nel. Whether or not it might be effective as a sole treatment is unknown, but past attempts to treat parkinsons disease with nonselective maoi monotherapy are reported to have been unsuccessful. Levodopa, the metabolic precursor of dopamine, relieves symptoms but does not prevent continued cell death. Comparison between bromocriptine and selegiline in treatment. Estadio 2 afectacion bilateral o axial linea media. Efficacy of rasagiline in early parkinsons disease. Selegiline, also known as ldeprenyl and sold under the brand names eldepryl and emsam among others, is a medication which is used in the treatment of parkinsons disease and major. Selegiline hydrochloride monograph for professionals. Parkinson s disease involves the progressive degeneration of dopamine neurons in the extrapyramidal motor system. Investigation by parkinsons disease research group of united kingdom into excess mortality seen with combined levodopa and selegiline treatment in patients with early, mild parkinsons disease.